Expected benefits and achievements
- The establishment of a multidisciplinary consortium within an EU framework to study an important multifactorial disease of pigs that affects food safety and quality. It is expected that the wide range of disciplines within this consortium will provide a much needed platform of expertise within and beyond the lifetime of this project that can quickly react to other new emerging mulifactorial disease syndromes in pigs that threaten food safety and quality.
- A reduction in the load of secondary bacterial infections in pig herds, accompanied by a consequential reduction in the use of antibiotic therapy and risk of acquired antibiotic resistance.
- An increase in the quality and safety of food product derived from pigs.
- Establishment of a common standardised and harmonised reagent bank for the study of PCVD
- The identification of common co-factors or triggers that lead to full clinical development of PCVD.
- Determination of the molecular mechanisms of PCV2 replication and pathogenesis and the early replication sites of PCV2 in pigs.
- Elucidation of the possible role of pig genetics, nutrition and other environmental factors in the full clinical expression of PCVD
- Elucidation of the early interactions of PCV2 with the porcine immune system relevant to susceptibility or resistance to PCVDs.
- A possible explanation as to why sporadic PCVD suddenly changed to a global epizootic of PCVD.
- Effective and consistent control measures for PCVD that can be applied across all EU member states.
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